Key Takeaways
- XERF treatment is a dual-frequency monopolar RF lift that delivers 6.78 MHz and 2 MHz energy in a single pulse to tighten skin and stimulate collagen.
- Thermage and Oligio are also monopolar RF devices, and XERF stands apart by adding a second, lower frequency that spreads heat more broadly into deeper tissue.
- At TALISA Clinic, XERF is performed by a doctor and starts at 25,000 baht for 300 shots, with full results usually visible within two to three months.
XERF treatment is a nonsurgical skin tightening procedure that uses dual-frequency monopolar RF energy to heat the deeper layers of the skin and prompt collagen to tighten and renew. During a single pulse, the device emits energy at 6.78 MHz followed by 2 MHz, distinguishing it from single-frequency RF devices. This product is used on the face, cheeks, jawline, beneath the chin, and around the eyes to reduce sagging, fine lines, and improve facial definition. This guide details how it functions, compares it with Thermage and Oligio, and outlines what to anticipate during a session.
What XERF Is and What It Treat
The XERF RF system is made by Cynosure Lutronic. It is sometimes searched as XERF laser, although it uses radiofrequency energy rather than laser light. A recent retrospective study of a single XERF session reported improvements in facial skin laxity, wrinkle severity, skin evenness and pore size, along with gradual elevation of the eyebrows and upper eyelids. The authors described the results as preliminary, and treatment was well tolerated with only mild, short-lived side effects.
TALISA Clinic uses XERF to address:
- Sagging cheeks and a softening jawline.
- Fullness under the chin.
- Nasolabial folds and fine lines.
- Laxity around the eyes.
How Monopolar RF Skin Tightening Works
Radiofrequency converts electrical energy into heat within the dermis. When collagen is heated to the right range, its fibers contract, which gives an immediate tightening effect. The heat also triggers a healing response that builds new collagen and elastin over the following months.
Using a single active electrode on the skin alongside a grounding pad located elsewhere on the body, monopolar RF completes the circuit and allows energy to travel as deep as about 20 mm into the tissue. Cooling the surface shields the skin’s outer layer as heat accumulates underneath. Bipolar and multipolar RF use two or more electrodes on the skin’s surface, keeping the energy more superficial and confined.
XERF belongs to the monopolar category, the group designed for deeper tightening.
Demand for RF skin tightening in Bangkok reflects this balance: a visible lift and firmer skin without incisions, needles or a long recovery.
What Is XERF and How Is It Different From Thermage and Oligio?
Thermage, Oligio and XERF are all monopolar RF options, each with its own characteristics:
Feature | XERF | Oligio | Thermage |
RF type | Dual-frequency monopolar RF (6.78 MHz and 2 MHz) | Monopolar RF (6.78 MHz) | Monopolar RF |
How energy spreads | Adds 2 MHz energy that reaches more broadly into the fat layer | Localized heating in the dermis and fibrous tissue | Heating in the dermis and deeper tissue |
Comfort in studies | Well tolerated, with mild and transient side effects | Average pain score of 3-8, with built-in cryogen cooling | Comfort depends on settings and cooling |
Result profile | Tightening plus improvements in skin quality | Mild to moderate improvement in lower face laxity | Gradual tightening as collagen remodels |
Research on the two frequencies helps explain the difference. Computer modeling found that 2 MHz energy produces broader and deeper heating within fat, while 6.78 MHz energy creates more localized heating along the fibrous bands of tissue. XERF combines both in one pulse, which suits patients who want tightening along with a slimmer contour. None of these devices is universally better, and each is chosen to match the concern. Thermage is included here for comparison and is not offered at TALISA Clinic.
Who Is a Good Fit for XERF?
XERF tends to suit patients who are noticing early changes and want to act before they progress. Typical candidates include those with:
- Early skin laxity along the cheeks, jawline or under the chin.
- A preference for prevention, maintaining firmness before deeper sagging sets in.
- A wish to tighten skin without surgery or extended downtime.
- Previous Ulthera or Oligio treatment and a goal of maintaining results.
Patients with more advanced sagging may be advised to consider a deeper lifting treatment first, or a combination.
XERF can also be planned alongside focused ultrasound. At TALISA Clinic, a package of XERF 300 shots with Ultraformer 400 shots is available at 29,990 baht for patients who want tightening and deeper lifting together.
Whether XERF is suitable for the skin and objective is determined by a doctor’s assessment. Individuals who are pregnant, possess implanted electronic devices or metal implants in the treatment region, or have an ongoing skin infection should mention this during consultation prior to any RF treatment.
What to Expect From a XERF Treatment
The session follows a clear sequence:
- Consultation. The doctor reviews skin laxity, fat distribution and goals, then plans the areas and number of shots.
- Preparation. The skin is cleansed, and a grounding pad is placed to complete the monopolar circuit.
- Treatment. The handpiece delivers energy across each zone while patients feel warmth beneath the skin.
- Aftercare. There are no wounds, any mild redness is usually short-lived, and most patients return to daily activities right away.
Around 20 to 30 percent of the change is often visible right after treatment, with full results at two to three months that typically last about a year, according to TALISA Clinic’s treatment experience.
Firmer Skin Through Two Frequencies
XERF brings two monopolar RF frequencies into a single treatment, combining collagen tightening with broader heating in deeper tissue. Matching the device to the skin’s needs is what produces the most natural result.
TALISA Clinic is a doctor-led aesthetic clinic where every XERF session is planned and performed by a doctor. XERF starts at 25,000 baht for 300 shots or 49,000 baht for 600 shots, and the clinic also offers Oligio X, Ultraformer and Ultherapy Prime, so the doctor can recommend the device that best fits each patient.
Book a consultation today to find out whether XERF is right for the skin and goals:
- LINE OA : @TALISAclinic
- Instagram : TALISAclinic
- Facebook : TALISA Clinic
- Tel : 062-486-3626
References
- Objective and subjective retrospective evaluation of XERF, a novel single-shot dual-frequency non-invasive monopolar radiofrequency. Retrieved October 5, 2026, from pubmed.ncbi.nlm.nih.gov/42611100
- The Landscape of Radiofrequency Technology for Skin Rejuvenation. Retrieved October 5, 2026, from pmc.ncbi.nlm.nih.gov/articles/PMC12743727
- Computational modeling and histologic analysis of 6.78- and 2-MHz monopolar radiofrequency-induced thermal reactions. Retrieved October 5, 2026, from pmc.ncbi.nlm.nih.gov/articles/PMC12662868
- Efficacy and Safety of Monopolar Radiofrequency for Treatment of Lower Facial Laxity in Asians. Retrieved October 5, 2026, from pmc.ncbi.nlm.nih.gov/articles/PMC9588109
Frequently Asked Questions About XERF Treatment (FAQs)
Q: What is XERF and how is it different from Thermage and Oligio?
A: XERF is a dual-frequency monopolar RF treatment that delivers 6.78 MHz and 2 MHz energy in a single pulse. Thermage and Oligio are also monopolar RF devices. The added 2 MHz energy in XERF spreads heat more broadly into deeper tissue, which supports tightening along with facial contouring.
Q: Is XERF a laser?
A: No. XERF uses radiofrequency energy rather than laser light. It heats the deeper layers of the skin to tighten collagen and stimulate new collagen over time.
Q: Does XERF hurt?
A: Patients usually feel warmth beneath the skin during treatment. A retrospective study reported that XERF was well tolerated, with only mild and transient side effects.
Q: How long do XERF results last?
A: At TALISA Clinic, part of the change is often visible right after treatment, with full results at two to three months that typically last about a year. Results vary from person to person.
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